Recent News & Events

Patients with bone marrow diseases can get bone marrow transplants. However, this treatment method usually causes uncomfortable and damaging side effects such as fatigue, nausea and fertility loss. To improve the treatment of blood and immune disorders, researchers at the University of California, San Diego have engineered a synthetic bone implant that resembles real bone and produces healthy, functional blood.

Technologies for medical implants continue to evolve at a fast pace. Pacemakers are one example of an implant that just keeps getting smaller. However, we still have to use traditional batteries to power them. This is why researchers have revealed a "biological supercapacitor" that uses the human body to power battery-free pacemakers and other medical implants that can potentially last a lifetime.

Check out the 2017 National Institutes of Health (NIH) RCDC funding estimates for scientific research by category. The RCDC is a system that reports on the research grants, contracts and funds issued by the NIH. It gives scientists and other members of the public a way to see how the agency uses tax dollars to fund health projects and studies.

The Commons is a shared virtual space where scientists can work with the digital objects of biomedical research, i.e. it is a system that will allow investigators to find, manage, share, use and reuse data, software, metadata and workflows. It will be a complex ecosystem and thus the realization of the Commons will require the use, further development and harmonization of several components.

In the life sciences, healthcare, or chemistry, an important type of equipment is the centrifuge. These precision machines, when properly operated and maintained, can last ten years or more. Although no organization is eager to spend money on replacement equipment, it will eventually become necessary.

Blood transfusions save lives but blood isn't always available, especially in pre-hospital environments, because it requires refrigeration. Even with refrigeration, blood expires after 42 days, so you must routinely replace it. Scientists have researched the possibility of synthetic blood (also called artificial blood or blood surrogates) for years, and researchers at Ohio State University and Washington University in St. Louis may have found at least a temporary solution: powdered blood.

SEARCHBreast is a tissue prototype database that that allows breast cancer researchers everywhere to share their in silico, in vitro and in vivo animal models so that other researchers can search for and use them. The benefits of SEARCHBreast are that it adds value to already funded research, makes new research projects cheaper and accelerates the entire process. For example, one genetic model for breast cancer could require a comprehensive breeding program to generate one mouse that has the necessary phenotype. This program may take up to 18 months to produce results, and it will be very expensive. With access to the necessary tissues through SEARCHBreast, the amount of time for the research drops to a matter of weeks, which considerably reduces the cost. Additionally, it removes the need for more testing animals.

These benefits have already manifested through SEARCHBreast since its launch in 2014. The tissue prototype database has assisted the sharing of hundreds of tissue samples. As a result, 400 animals were spared.

While studying a rare congenital deformity that's affected 10 extended family members, Dr. Stefan Mundlos and his team made new discoveries about the human genome. During DNA analysis, the team of scientists found a new class of genetic mutations that sheds light on many mysterious diseases and helps scientists better understand how genetic coding works.

EasyApps^® software for quantifying DNA, RNA and Protein was developed to work intuitively with the DeNovix line of Spectrophotometers and Fluorometers which are compact, stand-alone instruments.

Pre-configured Apps ensure optimized workflows while simple to use Custom Method Apps enable researchers to quickly create and save methods. DeNovix software provides a multitude of choices for reviewing and exporting results.

You can voice your support for biomedical research by sending a pre-written letter. The NABR provides the letter and sends it for you so it only takes a few minutes (click "read more" below for the link). Your voice matters! We urge everyone to take this opportunity to contact President Trump, Mike Pence - VP and Congress to request their support. This is a tiny investment of your time that will pay significant dividends in terms of educating policy makers about the irreplaceable value of humane animal research.

“What is the O₂ concentration in a normoxic cell culture incubator?” This and other frequently asked questions in hypoxia research will be answered in this review. Our intention is to give a simple introduction to the physics of gases that would be helpful for newcomers to the field of hypoxia research. We will provide background knowledge about questions often asked, but without straightforward answers. What is O₂ concentration, and what is O₂ partial pressure? What is normoxia, and what is hypoxia? How much O₂ is experienced by a cell residing in a culture dish in vitro vs in a tissue in vivo? By the way, the O₂ concentration in a normoxic incubator is 18.6%, rather than 20.9% or 20%, as commonly stated in research publications. And this is strictly only valid for incubators at sea level.

Spatial Proximity Analyte Reagent Capture Luminescence (SPARCL) is useful for multiple applications, including enzyme immunoassays, high throughput binding assays, and protein-nucleic acid and protein-protein interactions. The differences between the two assays make SPARCL assays more cost effective and quicker to produce results than ELISAs.

Researchers from the University of California, San Diego (UCSD), concluded in a recent study that they could do so using a single adenosine molecule instead of a cocktail that involves a complicated process of many steps and elements that’s still required for other tissues like blood or skin. Read on to learn about their discovery and the life changing potential it holds for many people, like injured soldiers and victims of serious accidents.

The design of an Ultra-Low freezer should be optimized to protect the stored products from unnecessary exposure to warmer temperatures. To this end, most upright Ultra-Low freezers are designed with an inner door for each shelf within the unit, in addition to a heavy-duty outer door. This effectively creates enclosed storage compartments within the freezer to protect samples when one of the inner doors is opened.

Let’s face it, we’ve all wanted to know at some point or another what NASA has been researching into. Thankfully that day has come, because NASA has released all of their publicly funded research onto the internet via a platform called PubSpace.

Do you think that part-animal, part-human embryo research should be funded by the National Institute of Health (NIH)? Some may feel the question alone is an ethical or moral outrage while others will see it as the future and think of it with excitement. Regardless of which of these describes your thoughts and feelings, we can all agree that this issue is controversial.

Much of today’s focus on stem cell research revolves around human stem cell applications. However, one area of stem cell research that is showing real promise uses a companion animal’s own stem cells to solve health problems they’re having. Stem cell usage for companion animals is an exciting and developing research area and it’s even being used to help avoid surgery for many animals. In this article, you will find out where stem cells come from and the procedures implemented on various common companion animals.

Have you been searching for a method to separate a mixture of proteins and DNA? Or maybe you’re searching for a way to separate a mixture of different proteins or want to know how to separate a mixture of different DNA strands? If so, you’ve found what you have been looking for. After reading this article, you will understand how gel electrophoresis works and learn about the two most common types used to separate proteins and DNA- agarose gel electrophoresis and polyacrylamide gel electrophoresis SDS-PAGE.

How do you go about purchasing lab equipment? Are there specific procedures to follow? Is there a list of documented issues you should be aware of before buying equipment? For those of you in charge of purchasing equipment for a laboratory that have ever asked yourself questions like this, we’re going to show you how to navigate the marketplace and find the right equipment model, manufacturer, vendor and price.

“Shut the Sash not only saved energy and successfully changed behavior, but it created cohesion amongst researchers and boosted morale within the building. I am excited to see what MRB Green Team will tackle next,” said Cassi Reimer, KU’s energy conservation behavior specialist. Shut the Sash, an eight-week energy reduction program, focused on a single conservation behavior: the simple act of closing laboratory fume hoods. Besides the energy savings, they discovered other benefits of the program that were just as important. In fact, I don't know of any program that can claim better energy savings, safety or team building potential. Especially when you consider that this program can be used by almost every research lab in existance.